Joint models for longitudinal and survival data are now widely used in biostatistics to address a variety of etiological and predictive questions. Originally designed to simultaneously analyze the trajectory of a single marker measured repeatedly over time, and the risk of a single right-censored time-to-event, joint models now need to capture increasingly complex longitudinal information to adapt to in-depth medical research questions. After an introduction of the general joint modelling methodology, I discuss two extensions proposed to handle multivariate repeated marker information: one using a latent class approach and one using a latent degradation process approach.
Séminaire de mathématiques appliquées (archives)
Variational discretizations are known for preserving key physical invariants in a natural way, leading to long-time stability properties. In this talk I will present a discrete action principle for the Vlasov-Maxwell equations that applies in a general structure-preserving discrete framework.
In this framework the finite-dimensional electromagnetic potentials and fields are represented in a discrete de Rham sequence involving general Finite Element spaces, and the particle-field coupling is represented by a set of projection operators that commute with the differential operators.
Classical approaches to multiple testing grant control over the amount of false positives for a specific method prescribing the set of rejected hypotheses. In practice many users tend to deviate from a strictly prescribed multiple testing method and follow ad-hoc rejection rules, tune some parameters by hand, compare several methods and pick from their results the one that suits them best, etc. This will invalidate standard statistical guarantees because of the selection effect. To compensate for any form of such ”data snooping”, an approach which has garnered significant interest recently is to derive ”user-agnostic”, or post hoc, bounds on the false positives valid uniformly over all possible rejection sets; this allows arbitrary data snooping from the user.
Considering a Poisson process observed on a bounded, fixed interval, we are interested in the problem of detecting an abrupt change in its distribution, characterized by a jump in its intensity. Formulated as an off-line change-point problem, we address two distinct questions : the one of detecting a change-point and the one of estimating the jump location of such change-point once detected. This study aims at proposing a non-asymptotic minimax testing set-up, first to construct a minimax and adaptive detection procedure and then to give a minimax study of a multiple testing procedure designed for change-point localisation.
Mathieu Ribatet vous invite à une réunion Zoom planifiée.
Sujet : Séminaire de Fabrice Grela Heure : 9 févr. 2021 11:00 AM Paris
https://www.lebesgue.fr/fr/content/seminars-jrna2021
We study the approximation of multivariate functions on bounded domains with tensor networks (TNs). The main conclusion of this work is an answer to the following two questions that can be seen as different perspectives on the same issue: “What are the approximation capabilities of TNs?” and “What is the mathematical structure of approximation classes of TNs?”
We present a Bayesian model selection approach to estimate the intrinsic dimensionality of a high-dimensional dataset. To this end, we introduce a novel formulation of the probabilisitic principal component analysis model based on a normal-gamma prior distribution. In this context, we exhibit a closed-form expression of the marginal likelihood which allows to infer an optimal number of components. We also propose a heuristic based on the expected shape of the marginal likelihood curve in order to choose the hyperparameters. In non-asymptotic frameworks, we show on simulated data that this exact dimensionality selection approach is competitive with both Bayesian and frequentist state-of-the-art methods.
Mathieu Ribatet vous invite à une réunion Zoom planifiée.
Dans cet exposé, nous nous intéresserons à la résolution de problèmes de diffraction par formulation intégrale avec la présence de cavités elliptiques. Plus précisément, nous utiliserons une formulation intégrale classique, dite ``équation combinée des champs'' (Combined Field Integral Equation, ou CFIE) discrétisée par éléments de frontière et GMRes (Generalized Minimal Residual method) comme méthode de résolution itérative. L'objectif est de présenter une analyse de convergence de GMRes qui met en évidence la dépendance du nombre d'itérations en fonction de la fréquence lorsque la géométrie du problème contient une cavité elliptique. Ce travail est effectué en collaboration avec Alastair Spence et Euan Spence
Pour éviter les oscillations numériques liées à une approximation d’ordre élevé, nous suivons une approche basée sur des limiteurs permettant la préservation de la monotonie, tout en évitant la perte de précision au niveau des extrema réguliers; cette approche peut induire des contraintes sur le pas de temps, ce qui n’est pas souhaité pour des schémas semi-Lagrangiens, qui s’affranchissent en général justement de ce type de contrainte. Le schéma numérique que l’on propose est développé pour le transport à vitesse constante sur maillage périodique uniforme et na pas de contrainte sur le pas de temps. Nous donnons des applications à la simulation du système de Vlasov-Poisson.